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overexpress

A2

Pronunciation

UK

  • /ˌəʊvərɪksprˈɛs/

US

  • /ˌoʊvərɛksprˈɛs/

Description

Imagine something being turned up past the right level. To "overexpress" means to produce or show too much of something. The word is used most often in biology, where a gene or cell makes too much of a protein or other product. Scientists may overexpress a gene in the lab to study what it does, or they may describe a disease state in which a gene is overexpressed. Outside science, the word can sometimes describe feelings or reactions that are shown too strongly, but that use is less common. Think of it as going past the normal level until the result starts to stand out too much.

Examples

  1. 1

    Cancer cells

    These tumor cells overexpress a protein that helps them grow.

  2. 2

    Gene activity

    The gene is often overexpressed in several types of cancer.

  3. 3

    Lab research

    Researchers engineered yeast cells to overexpress the enzyme.

See also

verbproduce or cause unusually high levels of a gene product

Similar

  • overproduce
  • express at high levels

Shades of meaning

  • upregulate
  • induce
  • ectopically express

Contrast

Used with (collocations)

  • overexpress a gene
  • overexpress a protein
  • overexpressed in tumors

Word family

  • overexpression
  • overexpressed

Explore

  • gene expression
  • protein abundance

Forms and spellings

1 form open this card.

Main spelling

  • overexpress